Xp (short-arm) genes: Deletions or disruptions from important regions of the fresh short arm off brand new X chromosome (Xp11, Xp22.1-21.3) had been discussed in colaboration with gonadal dysgenesis and adorГЎvel BielorrГєssia senhoras you may prienorrhea.

Zfx (X-linked zinc digit protein): Situated on Xp22.1-21.step 3, this gene encodes a widely expressed proteins off unknown function. Zfx “knockout” mice is small, reduced rich, as well as have a lowered germ cell number throughout the ovaries and you will testes.

USP9X gene (ubiquitin-particular protease nine gene): It’s found on Xp11.cuatro, and its own device is generally conveyed in a lot of tissues. Inside the Drosophila, USP9X becomes necessary having eye invention and you may oogenesis, however, the character from inside the individual gonadal invention is actually unsure.

Xq (long-arm) genes: Studies of terminal deletions and you may autosomal translocations produced details about the need for numerous section located on the long arm of your own X chromosome. They might be Xq13-21, Xq22-25, and you can Xq26-twenty-eight.

FMR1 gene: This gene is based with the Xq27.step 3. Mutations within this gene represent expansions out-of CGG recite regarding supporter area of the FMR1 gene. 1-forty CGG repeats are thought typical, 40-60 repeats are considered a grey area, 60-200 repeats are considered premutation, and most two hundred CGG repeats represent full mutation. （更多…）